The outrageous singer has the honour of being the first act on stage at the Nokia Theatre in Los Angeles this weekend. She's looking forward to it, but refuses to give anything away.
''m really very honoured and excited to open the show. But I won't reveal anything; I want it to be a surprise,' she said.
't will be a continuation of everything I've been doing, and it will be exactly what they want. I'm pretty good at knowing what my fans want me to do.'
The VMAs are renowned for being opened by the biggest artists around. In 2003 Britney Spears and Christina Aguilera famously joined Madonna on stage and gave her a passionate kiss.
Gaga was asked to take part after telling organisers what her performance would be like.
't was even more exciting because I knew that it was based off the performance idea and MTV believing in me as an artist and they have, and I appreciate that, from the beginning. They always allowed me to do my version of pop music and not someone else's,' she told MTV News.
The star is nominated in four categories this year, including best female video for Born This Way and best choreography for Judas.
It's a good week for the singer, who has been named the most powerful female celebrity in the world by Forbes.
The publication has released its annual World's 100 Most Powerful Women list, and Gaga is the highest ranking celebrity at number 11. Talk show queen Oprah Winfrey comes in at 14, while the top spot goes to German chancellor Angela Merkel.
With the VMAs just around the corner a number of stars have started recalling their favourite moments from past ceremonies.
Bruno Mars remembers being astounded by a medley of hits performed by Michael Jackson in 1995.
' think one of the tightest performances I've ever seen is Michael Jackson's VMAs. He did Dangerous into like Smooth Criminal,' he recalled. 'He just showed why he was the King of Pop. He's just not human. When you were watching it, he was doing dance moves you have never seen before. He made a moment.'
